The MET receptor tyrosine kinase in invasion and metastasis.
نویسندگان
چکیده
Various cytokines and soluble growth factors upon interaction with their membrane receptors are responsible for inducing cellular proliferation, differentiation, movement, and protection from anoikis (a planned suicide activated by normal cells in absence of attachment to neighboring cells or extracellular matrix (EMC)). Among those soluble factors a major position is exerted by hepatocyte growth factor (HGF) together with its receptor MET and macrophage-stimulating protein (MSP) in cooperation with its receptor RON.
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عنوان ژورنال:
- Journal of cellular physiology
دوره 213 2 شماره
صفحات -
تاریخ انتشار 2007